Ranking of South Carolina Counties By Population with American Ancestry in 2021
Updated on April 16, 2025.
Based on the US Census ACS-5Yrs estimates, in 2021, there were 495.30K people in South Carolina with American ancestry. Among all South Carolina counties, Charleston County had the highest population with American ancestry (65.37K), followed by Greenville County (38.16K), and York County (34.09K).
The chart and table below shows the top 10 counties with high number of people with American ancestry.
You can see similar information for other states and for other ancestry groups in South Carolina.
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Related Topics: South Carolina ACS-5Yrs Estimates, 2021 Topic List.
Data Source: US Census Bureau.
Ranking of South Carolina Counties By Population with American Ancestry in 2021
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| Rank | County | Population |
|---|---|---|
| 1 | Charleston County | 65372 |
| 2 | Greenville County | 38161 |
| 3 | York County | 34085 |
| 4 | Horry County | 33062 |
| 5 | Aiken County | 32512 |
| 6 | Spartanburg County | 30089 |
| 7 | Lexington County | 29535 |
| 8 | Anderson County | 22232 |
| 9 | Richland County | 21083 |
| 10 | Berkeley County | 17919 |
| 11 | Pickens County | 13390 |
| 12 | Beaufort County | 11653 |
| 13 | Florence County | 10955 |
| 14 | Dorchester County | 9867 |
| 15 | Cherokee County | 9684 |
| 16 | Georgetown County | 9340 |
| 17 | Lancaster County | 8923 |
| 18 | Oconee County | 8754 |
| 19 | Laurens County | 7354 |
| 20 | Sumter County | 6756 |
| 21 | Greenwood County | 6504 |
| 22 | Kershaw County | 6016 |
| 23 | Chester County | 6008 |
| 24 | Darlington County | 4341 |
| 25 | Barnwell County | 4312 |
| 26 | Dillon County | 3852 |
| 27 | Newberry County | 3788 |
| 28 | Edgefield County | 3698 |
| 29 | Orangeburg County | 3555 |
| 30 | Chesterfield County | 2934 |
| 31 | Marion County | 2857 |
| 32 | Saluda County | 2703 |
| 33 | Williamsburg County | 2667 |
| 34 | Colleton County | 2578 |
| 35 | Abbeville County | 2515 |
| 36 | Union County | 2478 |
| 37 | Marlboro County | 2293 |
| 38 | Bamberg County | 2101 |
| 39 | Fairfield County | 2030 |
| 40 | Clarendon County | 1825 |
| 41 | Hampton County | 1241 |
| 42 | Jasper County | 1235 |
| 43 | Lee County | 917 |
| 44 | Calhoun County | 824 |
| 45 | Allendale County | 770 |
| 46 | McCormick County | 532 |
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