US Number and Rate of Fatal Drug Overdose Deaths Involving Any non-opioid sedatives By State in 2021 (CDC)

Updated on February 2, 2026.

Based on data from the CDC, the overall number of fatal drug overdose deaths involving Any non-opioid sedatives in the US in 2021 was 11,064, and the age adjusted rate per 100,000 persons was 7.4. These overall values was based on data from 33 jurisdictions (i.e. states and DC).

Among all states with data, Pennsylvania had the highest number of fatal drug overdose deaths involving Any non-opioid sedatives (1,486), followed by North Carolina (864), Ohio (814), and Maryland (795).

In terms of the age-adjusted rate of fatal drug overdose deaths involving Any non-opioid sedatives per 100K persons, West Virginia had the highest (29.6), followed by Connecticut (19.6), and Maine (16.1).

The interactive chart below shows the number of fatal overdose deaths involving Any non-opioid sedatives by state for the jurisdictions with d ata. The table below shows the number and rate of fatal drug overdose deaths.

You can also see similar information for other types of drugs.

Note: A rate value of 9999 denotes that the value is suppressed. Rates based on less than 20 drug overdose deaths are suppressed to avoid presentation of unstable rates.

Related Topics: US CDC Topic List
Data Source: CDC (SUDORS).
See this for other years:
Number of Fatal Drug Overdose Deaths Involving Any non-opioid sedatives By State in 2021 (CDC)
1-250
251 - 500
501-1000
1001 - 1500
Over 1500
Number and Rate of Fatal Drug Overdose Deaths Involving Any non-opioid sedatives By State in 2021
Items per page:
0 of 0
State Number of Deaths Age Adjusted Rate Per 100K
Alaska 22 3.1
Arizona 311 4.4
Arkansas 160 5.6
Colorado 284 4.7
Connecticut 706 19.6
Delaware 30 3.1
Georgia 570 5.3
Hawaii 26 1.8
Iowa 66 2.2
Kansas 102 3.6
Kentucky 559 12.8
Maine 215 16.1
Maryland 795 12.8
Massachusetts 662 9.5
Michigan 452 4.6
Minnesota 230 4.2
Nebraska 54 3
Nevada 194 6.1
New Hampshire 30 2.3
New Jersey 781 8.5
New Mexico 138 6.8
North Carolina 864 8.4
Ohio 814 7.2
Oklahoma 108 2.9
Oregon 137 3.2
Pennsylvania 1486 11.8
Rhode Island 93 8.5
South Dakota 7 9999
Utah 214 6.9
Vermont 50 8.2
Virginia 372 4.3
West Virginia 496 29.6
District of Columbia 36 5.5