US Number and Rate of Fatal Drug Overdose Deaths Involving Illegally-made Fentanyls By State in 2023 (CDC)

Updated on February 2, 2026.

Based on data from the CDC, the overall number of fatal drug overdose deaths involving Illegally-made Fentanyls in the US in 2023 was 56,386, and the age adjusted rate per 100,000 persons was 25.2. These overall values was based on data from 42 jurisdictions (i.e. states and DC).

Among all states with data, New York had the highest number of fatal drug overdose deaths involving Illegally-made Fentanyls (4,844), followed by Ohio (3,647), Pennsylvania (3,625), and North Carolina (3,358).

In terms of the age-adjusted rate of fatal drug overdose deaths involving Illegally-made Fentanyls per 100K persons, West Virginia had the highest (66.4), followed by Delaware (46.4), and Tennessee (40.4).

The interactive chart below shows the number of fatal overdose deaths involving Illegally-made Fentanyls by state for the jurisdictions with d ata. The table below shows the number and rate of fatal drug overdose deaths.

You can also see similar information for other types of drugs.

Note: A rate value of 9999 denotes that the value is suppressed. Rates based on less than 20 drug overdose deaths are suppressed to avoid presentation of unstable rates.

Related Topics: US CDC Topic List
Data Source: CDC (SUDORS).
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Number of Fatal Drug Overdose Deaths Involving Illegally-made Fentanyls By State in 2023 (CDC)
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Number and Rate of Fatal Drug Overdose Deaths Involving Illegally-made Fentanyls By State in 2023
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State Number of Deaths Age Adjusted Rate Per 100K
Alabama 1025 21.3
Alaska 274 37.6
Arizona 1909 26.6
Arkansas 266 9.1
Colorado 1171 19.3
Connecticut 1130 31.3
Delaware 455 46.4
Georgia 1639 15
Hawaii 105 7.6
Illinois 2618 21
Indiana 1548 23.7
Iowa 177 5.9
Kansas 333 11.9
Kentucky 1537 35.7
Maine 466 35.1
Maryland 2061 33.1
Massachusetts 2015 28.8
Michigan 2111 21.6
Minnesota 941 17.1
Mississippi 383 13.7
Missouri 1370 23.1
Montana 90 8.5
Nebraska 54 2.8
Nevada 758 23.5
New Hampshire 364 27.1
New Jersey 2330 25
New Mexico 636 31.8
New York 4844 24.6
North Carolina 3358 31.9
Ohio 3647 32.3
Oklahoma 767 19.6
Oregon 1339 31.6
Pennsylvania 3625 29
Rhode Island 316 29.3
Tennessee 2785 40.4
Utah 293 9
Vermont 215 34.8
Virginia 1910 22.2
Washington 2634 33.5
West Virginia 1105 66.4
Wisconsin 1284 22.7
District of Columbia 498 77.1