US Number and Rate of Fatal Drug Overdose Deaths Involving Prescription Opioids By State in 2020 (CDC)

Updated on February 2, 2026.

Based on data from the CDC, the overall number of fatal drug overdose deaths involving Prescription Opioids in the US in 2020 was 9,093, and the age adjusted rate per 100,000 persons was 5.9. These overall values was based on data from 34 jurisdictions (i.e. states and DC).

Among all states with data, Pennsylvania had the highest number of fatal drug overdose deaths involving Prescription Opioids (992), followed by Ohio (604), Tennessee (554), and North Carolina (540).

In terms of the age-adjusted rate of fatal drug overdose deaths involving Prescription Opioids per 100K persons, West Virginia had the highest (21.5), followed by New Mexico (12.8), and Rhode Island (10.1).

The interactive chart below shows the number of fatal overdose deaths involving Prescription Opioids by state for the jurisdictions with d ata. The table below shows the number and rate of fatal drug overdose deaths.

You can also see similar information for other types of drugs.

Note: A rate value of 9999 denotes that the value is suppressed. Rates based on less than 20 drug overdose deaths are suppressed to avoid presentation of unstable rates.

Related Topics: US CDC Topic List
Data Source: CDC (SUDORS).
See this for other years:
Number of Fatal Drug Overdose Deaths Involving Prescription Opioids By State in 2020 (CDC)
1-250
251 - 500
501-1000
1001 - 1500
Over 1500
Number and Rate of Fatal Drug Overdose Deaths Involving Prescription Opioids By State in 2020
Items per page:
0 of 0
State Number of Deaths Age Adjusted Rate Per 100K
Alaska 45 6.3
Arizona 315 4.4
Colorado 404 6.8
Connecticut 325 9.1
Delaware 78 8.1
Georgia 376 3.5
Iowa 56 1.9
Kansas 66 2.4
Kentucky 410 9.5
Maine 116 9
Maryland 469 7.8
Massachusetts 490 7.1
Michigan 450 4.6
Minnesota 191 3.5
Mississippi 96 3.3
Montana 26 2.5
Nebraska 32 1.7
Nevada 197 6.3
New Hampshire 49 3.6
New Jersey 511 5.7
New Mexico 258 12.8
North Carolina 540 5.2
Ohio 604 5.3
Oklahoma 105 2.8
Oregon 97 2.3
Pennsylvania 992 8
Rhode Island 106 10.1
South Dakota 13 9999
Tennessee 554 8.2
Utah 180 6.2
Vermont 37 6.5
Virginia 481 5.7
West Virginia 362 21.5
District of Columbia 62 9.5